Ever growing demand for in vitro fertilization despite stable biological fertility—a European paradox

E Te Velde, D Habbema, E Nieschlag… - European Journal of …, 2017 - Elsevier
Since the landmark discoveries of in vitro fertilization (IVF) in 1978 and its main variant intra
cytoplasmic sperm injection (ICSI) in 1992–jointly called 'IVF'unless mentioned separately–
the use of IVF has grown tremendously in high-income countries; in this study we mainly
focus on Europe. Between 1997 and 2011 almost 900,000 IVF-infants were born in Europe
and this number must have surpassed over 1, 4 million by now [1]. Worldwide over 5 million
IVF babies were born by the end of 2013, mostly in high-income countries [2]. IVF is by far …
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